Retrospective Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Sep 28, 2020; 26(36): 5437-5449
Published online Sep 28, 2020. doi: 10.3748/wjg.v26.i36.5437
Table 1 Baseline characteristics comparing the standard infusion (n = 169) and rapid infusion (n = 129) cohorts
VariableStandard, n (%)Rapid, n (%)P value
Male sex (%)76 (45.0)55 (42.6)0.72
Age (yr) (median, range)39 (20-88)42 (18-86)0.86
Low BMI (< 22 kg/m2)17 (10.1)13 (10.1)0.84
High BMI (> 30 kg/m2)28 (16.6)31 (24.0)0.14
Current smoker28 (16.6)26 (20.2)0.45
Disease duration (yr) (median, range)7 (0-49)5 (0-36)0.78
Disease type
CD126 (74.6)114 (88.4)< 0.01
UC43 (25.4)14 (10.9)< 0.01
Indeterminate0 (0.0)1 (0.8)0.43
Extra-intestinal manifestation(s) documented46 (27.2)29 (22.5)0.42
Psychiatric comorbidity documented24 (14.2)45 (34.9)< 0.01
Concomitant medications
Corticosteroid11 (6.5)11 (8.5)0.51
Immunomodulator114 (67.5)104 (80.6)0.01
Thiopurine91 (79.8)70 (67.3)0.04
Thiopurine ADR32 (35.2)32 (45.7)0.20
Methotrexate23 (20.2)34 (32.7)0.04
Methotrexate ADR12 (52.2)10 (29.4)0.10
Prior biologic21 (12.4)20 (15.5)0.40
Other anti-TNF18 (85.7)18 (90.0)1.00