Acute liver failure and death predictors in patients with dengue-induced severe hepatitis

Table 5 Factors associated with the risk of death among dengue-induced severe hepatitis patients with acute liver failure

Factors	Dengue survivors (n = 7)	Dengue nonsurvivors (n = 10)	Odd ratio of death	P value
Presence of DSS, n (%)	3 (42.9)	8 (80.0)	5.3	0.128
Concurrent extrahepatic organ failure, n (%)
Systemic bleeding	5 (71.4)	10 (100.0)	9.6	0.154
Bacterial sepsis	2 (28.6)	6 (60.0)	3.8	0.211
Renal failure	5 (71.4)	9 (90.0)	3.6	0.341
ARDS	1 (14.3)	3 (30.0)	2.6	0.461
DIC	2 (28.6)	5 (50.0)	2.5	0.382
Multiple (≥ 2) extrahepatic organ failure, n (%)	3 (42.9)	8 (80.0)	5.3	0.128
Liver-specific treatment, n (%)
Any treatment1	5 (71.4)	5 (50.0)	0.4	0.382
Intravenous NAC	4 (57.1)	4 (40.0)	0.5	0.488
Artificial liver support	2 (28.6)	2 (20.0)	0.6	0.683

¹In comparison with conservative treatment. ARDS: Acute respiratory distress syndrome; DIC: Disseminated intravascular coagulation; NAC: N-acetylcysteine; DSS: Dengue shock syndrome.