Retrospective Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. Aug 28, 2020; 26(32): 4833-4845
Published online Aug 28, 2020. doi: 10.3748/wjg.v26.i32.4833
Table 4 Univariate and multivariate analysis of factors associated with extrahepatic metastasis
Univariate analysis
Multivariate analysis
OR (95%CI)P valueOR (95%CI)P value
BCLC stage (0 vs A, B)2.93 (1.38–6.20)0.003
mUICC stage (I vs II, III)2.04 (1.04–3.96)0.034
Post-RFA complication (fever, abscess)2.78 (1.31–5.92)0.050
Presence of intra-hepatic recurrence48.8 (6.68–356.63)0.000
ALP > 97 U/L2.29 (1.23-4.26)0.008
1st recurrence free survival < 2 yr2.88 (1.54-5.38)0.0012.44 (1.16-5.14)0.019
Ratio of ablation zone and tumor size < 23.84 (1.76-8.39)0.0013.33 (1.34-8.27)0.010
Presence of tumoral thrombosis2.57 (1.13-5.84)0.024
AFP > 400 IU/mL at 1st recurrence4.52 (2.03-10.07)0.0003.35 (1.33-8.43)0.010
mUICC stage > 2 at 1st recurrence2.49 (1.22-5.06)0.012