Mucosal-associated invariant T cells in hepatitis B virus-related liver failure

Table 1 Characteristics of healthy controls and chronic hepatitis B and hepatitis B virus-related liver failure patients

Clinical parameters	HC	CHB	HBV-related liver failure
Number	40	48	55
Age in yr	47.05 ± 14.70	41.63 ± 13.08	47.89 ± 11.04
Male, n	24	27	37
ALT in U/L	16.55 ± 5.43	327.52 ± 312.57	549.60 ± 686.13bc
AST in U/L	22.95 ± 5.70	176.58 ± 208.19	487.55 ± 571.49be
Total bilirubin in μmol/L	12.48 ± 3.23	25.65 ± 43.43	302.52 ± 144.84bf
Albumin in g/L	42.98 ± 2.32	42.36 ± 3.99	31.01 ± 4.06bf
Prealbumin in mg/L	NA	109.17 ± 68.43	174.09 ± 81.47d
Cholinesterase in U/L	NA	6536.11 ± 2543.80	3214.65 ± 1663.35f
Prothrombin time in s	NA	NA	25.44 ± 8.30
International normalized ratio	NA	NA	2.22 ± 0.74
Prothrombin activity as %	NA	NA	29.87 ± 9.09
Leucocyte as × 109/L	5.77 ± 1.60	5.01 ± 1.30	6.74 ± 4.18c
Lymphocyte number as × 109/L	2.64 ± 0.73	1.70 ± 0.60	3.08 ± 5.40
Blood platelets as × 109/L	194.68 ± 41.53	157.52 ± 67.53	97.96 ± 52.06bf
Creatinine in μmol/L	NA	63.08 ± 13.24	96.69 ± 123.50
hs-CRP in mg/dL	NA	NA	20.04 ± 29.97
Log HBV DNA in IU/mL	NA	6.81 ± 1.33	5.27 ± 1.79f

All data are presented as mean ± SD.

^bP < 0.0001 vs HC.

^cP < 0.05.

^dP < 0.01.

^eP < 0.001.

^fP < 0.0001. vs CHB. ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; CHB: Chronic hepatitis B; HBV: Hepatitis B virus; HC: Healthy controls; hs-CRP: Hypersensitive C-reactive protein; NA: Not applicable.