Efficacy and safety of lenvatinib for patients with advanced hepatocellular carcinoma: A retrospective, real-world study conducted in China

Table 3 Efficacy of lenvatinib in patients with advanced hepatocellular carcinoma

Investigator review according to RECIST 1.1	ALL (n = 54)	HBV-related HCC (n = 40)	P value
Progression-free survival (d, 95%CI)	168 (130-205)	175 (124-226)	0.250
Time to progression (d, 95%CI)	153 (116-189)	156 (126-186)	0.520
Objective response	22%	25%	0.753
Complete response	0	0	-
Partial response	12	10	-
Stable disease	36	26	0.866
Progressive disease	6	4	-
Disease control rate	88%	90%	0.863
Decreased AFP predicts tumor reduction
Se	56.7%	53.8%	-
Sp	83.3%	85.7%	-

HBV: Hepatitis B virus; RECIST 1.1: Response Evaluation Criteria in Solid Tumors version 1.1; AFP: Alpha-fetoprotein; Se: Sensitivity; Sp: Specificity; CI: Confidence interval.