Nucleotide excision repair pathway gene polymorphisms are associated with risk and prognosis of colorectal cancer

Table 5 Association between host factors and the overall survival of colorectal cancer patients

Factor	CRC patients	Death	MST (M)	P value
Total	n = 565	n = 95
Gender				0.862
Male	384	63	46.61
Female	181	32	47.11
Age (yr)				0.127
≤ 60	322	46	47.91
> 60	243	49	44.71
Smoking				0.111
Ever Smoker	180	23	48.71
Never Smoker	383	72	45.91
Drinking				0.157
Drinker	107	14	49.31
Non-drinker	456	81	46.11
TNM stage				< 0.001
I + II	336	23	52.11
III + IV	223	69	48
Macroscopic type				< 0.001
Protrude type	104	5	53.41
Ulcerative/Invasive type	458	90	45.21
Histological type				< 0.001
High/Middle differentiation	367	40	50.21
Low differentiation	196	55	39.31
Depth of invasion				< 0.001
T1 + T2	114	6	53.41
T3 + T4	450	89	44.91
Growth mode				< 0.001
Nest	236	18	52.11
Invasion	326	77	42.61
Lymphatic metastasis				< 0.001
Positive	217	68	47
Negative	342	24	52.01

CRC: Colorectal cancer; MST (M): Median survival time (mo).

¹Mean survival time was provided when MST could not be calculated. Statistically significant associations are in bold (P < 0.05).