Role of nutritional status and nutritional support in outcome of hepatitis B virus-associated acute-on-chronic liver failure

Table 3 Baseline characteristics of hepatitis B virus-associated acute-on-chronic liver failure patients enrolled in Study 2, n (%)

Characteristic	Nutritional support	None-nutritional support	P value
n	234	207
Age (yr)	46.7 ± 10.8	47.5 ± 11.6	0.454
Male	202 (86.3)	172 (83.9)	0.345
HBeAg positive	98 (41.9)	96 (46.4)	0.342
HBV-DNA (log10 IU/mL)	6.14 (1.85, 8.13)	6.54 (1.53, 8.71)	0.097
PLT (109/L)	120.2 ± 49.1	112.6 ± 52.6	0.117
ALT (IU/L)	680 (421, 1191)	652 (447, 1352)	0.243
AST (IU/L)	592 (313, 980)	613 (320, 1014)	0.381
ALB (g/L)	33.6 ± 4.9	34.1 ± 5.2	0.299
TBIL (µmol/L)	274.1 (166.1, 588.7)	291.5 (162.5, 604.3)	0.227
PTA (%)	34 (14, 40)	32 (11, 40)	0.135
INR	2.46 ± 0.18	2.49 ± 0.21	0.107
BUN (mmol/L)	6.1 (3.1, 8.7)	6.4 (3.2, 9.2)	0.295
Cr (μmol/L)	73 (66, 104)	76 (59, 98)	0.530
SBP	124 (53.0)	106 (51.2)	0.708
Hepatic encephalopathy	97 (41.5)	82 (39.6)	0.695
Hepatorenal syndrome	24 (10.3)	19 (9.2)	0.703
MELD scores	25.4 ± 4.8	26.1 ± 5.2	0.142
Artificial extracorporeal liver support	141 (60.3)	124 (59.9)	0.940

Data presented as mean ± SD, median (IQR) or n (%). ALB: Albumin; ALT: Alanine aminotransferase; AST: Aspartate aminotransferase; BUN: Blood urea nitrogen; Cr: Creatinine; HBeAg: Hepatitis B e antigen; INR: International normalized ratio; SBP: Spontaneous bacterial peritonitis; MELD: Model for end-stage liver disease; PLT: Platelet; PTA: Prothrombin activity; TBIL: Total bilirubin level.