Celecoxib attenuates hepatocyte apoptosis by inhibiting endoplasmic reticulum stress in thioacetamide-induced cirrhotic rats

Figure 3 Celecoxib inhibits endoplasmic reticulum stress. A: Hepatocytes in the thioacetamide (TAA) and TAA + celecoxib groups (transmission electron microscopy, × 6000-10000); B: Hepatic glucose-regulated protein 78 and CCAAT/enhancer binding protein homologous protein expression measured by Western blot. n = 6/group; C and D: Quantitative Western blot results. ^aP < 0.05 vs TAA + celecoxib group; ^bP < 0.01 vs the control group. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase; GRP78: Glucose-regulated protein 78; CHOP: CCAAT/enhancer binding protein homologous protein. TAA: Thioacetamide.