Type I and type II Helicobacter pylori infection status and their impact on gastrin and pepsinogen level in a gastric cancer prevalent area

Table 1 Patient clinical data and Helicobacter pylori infection status

Groups	Total patients, n = 523	NAG,n = 213	NAGE,n = 96	PU,n = 94	CAG,n = 77	GC,n = 43	Hp (+),n = 402	Type IHp(+),n = 291	Type II Hp(+),n = 111	Hp (-),n = 121
Age in yr
mean ± SD	53.4 ± 11.6	50.3 ± 11.3a	53.7 ± 11.3	53.5 ± 13.1	58.0 ± 9.4a	59.6 ± 7.8c	53.7 ± 11.4	53.6 ± 11.3	53.9 ± 11.7	52.5 ± 12.1
28-40	76	57 (26.8%)	13 (13.5%)	16 (17.0%)	4 (5.2%)	0	57 (75.0%)	43 (56.6%)e	15 (19.7%)	18 (23.7%)
41-50	108	71 (33.3%)	21 (21.9%)	17 (18.1%)	7 (9.1%)	6 (14.0%)	78 (72.2%)	55 (50.9%)e	23 (21.3%)	30 (27.8%)
51-60	191	54 (25.3%)	36 (37.5%)	30 (31.9%)	32 (41.6%)	21 (48.8%)	150 (78.5%)	108 (56.5%)e	42 (22.0%)	41 (21.5%)
61-80	148	31 (14.6%)	26 (27.1%)	31 (33.0%)	34 (44.2%)	16 (37.2%)	116 (78.4%)	85 (57.5%)e	31 (20.9%)	32 (21.6%)
Gender
Male	305	105 (49.3%)	52 (54.2%)	68 (70.2%)g	53 (68.8%)g	27 (58.3%)g	234 (76.7%)	167 (54.8%)i	67 (22.0%)	71 (23.3%)
Female	218	108 (50.7%)	44 (45.8%)	26 (27.7%)	24 (31.2%)	16 (37.3%)	168 (77.1%)	124 (56.9%)i	44 (20.2%)	50 (22.9%)

Data are presented as n (%), unless otherwise indicted.

^aP < 0.05, mean age in CAG group was compared with NAG group;

^cP < 0.05, mean age in GC group was compared with NAG, NAGE groups;

^eP < 0.05, infection rate of type I H. pylori patients was compared with type II and H. pylori-negative patients in the same age groups;

^gP < 0.05, percentage in male groups was compared with female groups among PU, CAG, and GC groups;

ⁱP < 0.05, infection rate of type I H. pylori patients was compare with type II and Hp-negative patients in the same gender groups. CAG: Chronic atrophic gastritis; GC: Gastric cancer; H. pylori: Helicobacter pylori; NAG: Non-atrophic gastritis; NAGE: Non-atrophic gastritis with erosion; PU: Peptic ulcer; SD: Standard deviation.