Transjugular intrahepatic portosystemic shunt for pyrrolizidine alkaloid-related hepatic sinusoidal obstruction syndrome

doi:10.3748/wjg.v26.i24.3472

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 26, Issue 24

This Article

(303)

(274)

(0)

(14)

(1)

(6845)

(12)

Peer-Review Report of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Supplementary Materials of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

- Full Article with Cover (PDF)
- Full Article (XML)

Retrospective Study

World J Gastroenterol. Jun 28, 2020; 26(24): 3472-3483
Published online Jun 28, 2020. doi: 10.3748/wjg.v26.i24.3472

Table 1 Baseline clinical characteristics of the patients in the two groups

Characteristic	TIPS group (n = 37)	Conservative treatment group (n = 17)	P value
Gender (male/female)	28/9	11/6	0.403
Age (yr)	62.30 ± 10.91	60.18 ± 15.37	0.563
Onset-to-treatment time (d)	28.57 ± 15.26	26.18 ± 12.44	0.535
MELD score	12.13 ± 5.32	12.76 ± 4.96	0.683
Early therapeutic regimen
Reduced glutathione	37 (100)	17 (100)	NA
Ademetionine	37 (100)	17 (100)	NA
Diuretics	37 (100)	17 (100)	NA
Low molecular weight heparin	37 (100)	17 (100)	NA
Glucocorticoids	11 (29.73)	6 (35.29)	0.757
Antibacterial drugs,	23 (62.16)	12 (70.60)	0.549
Clinical symptoms on admission
Ascites (yes/no)	37/0	17/0	NA
Hepatomegaly (yes/no)	26/11	10/7	0.407
Hepatalgia (yes/no)	15/22	7/10	0.965
Peritonitis (yes/no)	7/30	2/15	0.512
Loss of appetite (yes/no)	34/3	15/2	0.667
Gastrointestinal bleeding (yes/no)	1/36	0/17	0.494
Weight gain (yes/no)	12/25	6/11	0.836
Laboratory indicators at 2 wk
Total bilirubin (μmol/L)	53.3 (39.8)	53.6 (45.0)	0.904
Direct bilirubin (μmol/L)	32.4 (32.6)	37.4 (47.0)	0.520
Alanine transaminase (U/L)	45.0 (69.0)	55.0 (86.0)	0.342
Aspartate transaminase (U/L)	65.0 (48.0)	62.0 (89.0)	0.628
Gamma-glutamyl transferase (U/L)	125.0 (90.0)	91.0 (94.0)	0.099
Alkaline phosphatase (U/L)	112.6 (60.0)	95.0 (91.0)	0.087
Albumin (g/L)	31.32 ± 3.38	31.95 ± 4.92	0.588
Prothrombin time (s)	15.81 ± 3.64	16.75 ± 2.28	0.342
White blood cell count (10⁹/L)	6.75 ± 3.05	6.66 ± 2.20	0.913
Neutrophil proportion (%)	64.19 ± 12.16	64.39 ± 10.70	0.955
Red blood cell count (10¹²/L)	4.91 ± 0.81	4.49 ± 0.63	0.064
Platelet count (10⁹/L)	108.0 (49.0)	90.0 (68.0)	0.165
Blood urea nitrogen (mmol/L)	6.8 (3.4)	5.6 (4.3)	0.252
Creatinine (μmol/L)	67.6 (32.0)	75.0 (35.0)	0.780
Maximum depth of ascites (mm)	95.22 ± 22.58	81.65 ± 26.29	0.057

Data are presented as mean ± standard deviation, median (interquartile range) or n (%). MELD: Model for end-stage liver disease; TIPS: Transjugular intrahepatic portosystemic shunting; NA: Not available.

Full Size Table

Citation: Zhou CZ, Wang RF, Lv WF, Fu YQ, Cheng DL, Zhu YJ, Hou CL, Ye XJ. Transjugular intrahepatic portosystemic shunt for pyrrolizidine alkaloid-related hepatic sinusoidal obstruction syndrome. World J Gastroenterol 2020; 26(24): 3472-3483
URL: https://www.wjgnet.com/1007-9327/full/v26/i24/3472.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i24.3472

Zhou CZ, Wang RF, Lv WF, Fu YQ, Cheng DL, Zhu YJ, Hou CL, Ye XJ. Transjugular intrahepatic portosystemic shunt for pyrrolizidine alkaloid-related hepatic sinusoidal obstruction syndrome. World J Gastroenterol 2020; 26(24): 3472-3483 [PMID: 32655270 DOI: 10.3748/wjg.v26.i24.3472]

All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.