Multiphase computed tomography radiomics of pancreatic intraductal papillary mucinous neoplasms to predict malignancy

Table 3 Noncontrast phase radiomics features (P < 0.05) for the intraductal papillary mucinous neoplasm study cohort

Variables	SD	P value	OR per 1 SD increase	95%CI lower	Upper	AUC (95%CI)
Log2 (energy_HU)	2.511	0.002	4.33	1.69	11.11	0.82 (0.689-0.951)
Median_HU	10.72	0.003	4.43	1.65	11.85	0.794 (0.658-0.929)
Log2 (GLCM_row_mean)	1.129	0.007	9.21E+39	8.82E+10	9.62E+68	0.785 (0.648-0.923)
Root_mean_square	10.38	0.011	8.03	1.61	40	0.779 (0.641-0.917)
Mean_HU	11.22	0.006	3.73	1.47	9.46	0.773 (0.631-0.916)
Log2 (surface_area_mm2)	1.592	0.006	3.18	1.4	7.22	0.765 (0.613-0.918)
Volumetric_length_mm	25.05	0.007	4.46	1.5	13.26	0.759 (0.602-0.916)
Compactness2_mm	0.144	0.017	0.38	0.17	0.84	0.749 (0.59-0.908)
Sphericity_mm	0.076	0.034	0.39	0.17	0.93	0.749 (0.59-0.908)
Transverse_length_mm	18.14	0.012	2.99	1.28	6.98	0.741 (0.585-0.896)
GLCM_entropy	1.642	0.01	3.04	1.31	7.05	0.737 (0.581-0.893)
Log2 (GLCM_energy)	0.764	0.011	0.33	0.14	0.78	0.735 (0.581-0.889)
Log2 (GLCM_ASM)	1.527	0.011	0.33	0.14	0.78	0.735 (0.581-0.889)
Compactness1_mm	30.29	0.047	2.27	1.02	5.05	0.729 (0.568-0.89)
Antpost_length_mm	15.85	0.04	2.35	1.04	5.3	0.715 (0.55-0.879)
Log2 (max_HU)	1.043	0.043	2.94	1.04	8.28	0.712 (0.559-0.864)
Surface_area_to_volume_ratio_mm	0.2	0.019	0.38	0.17	0.84	0.694 (0.527-0.862)
Cranialcaudal_length_mm	14.55	0.043	2.03	1.03	4	0.687 (0.521-0.854)

SD: Standard deviation; OR: Odds ratio; CI: Confidence interval; AUC: Area under the curve; HU: Hounsfield units; GLCM: Gray level co-occurrence matrix; ASM: Angular second moment; Max: Maximum.