Medications in type-2 diabetics and their association with liver fibrosis

Table 1 Demographic and clinical characteristics

Factor	Overall (n = 1183)		Fibrosis 0-2 (n = 802)		Fibrosis 3-4 (n = 381)		P value
	n	Statistics	n	Statistics	n	Statistics
Age at biopsy (yr)	1183	52.0 ± 11.6	802	50.3 ± 11.5	381	55.5 ± 11.1	< 0.0011
Gender	1183		802		381		0.0173
Female		777 (65.7)		545 (68.0)		232 (60.9)
Male		406 (34.3)		257 (32.0)		149 (39.1)
Race	1183		802		381		< 0.0013
Caucasian		1007 (85.1)		665 (82.9)		342 (89.8)
African American		109 (9.2)		97 (12.1)		12 (3.1)
Other		67 (5.7)		40 (5.0)		27 (7.1)
Smoking	1173		795		378		0.0413
Never		675 (57.5)		477 (60.0)		198 (52.4)
Former		426 (36.3)		274 (34.5)		152 (40.2)
Current		72 (6.1)		44 (5.5)		28 (7.4)
BMI	1183	35.4 ± 8.3	802	35.4 ± 8.1	381	35.2 ± 8.8	0.571
BMI group	1183		802		381		0.592
Normal weight		74 (6.3)		41 (5.1)		33 (8.7)
Overweight		233 (19.7)		161 (20.1)		72 (18.9)
Obese		596 (50.4)		413 (51.5)		183 (48.0)
Severely obese		280 (23.7)		187 (23.3)		93 (24.4)
SBP	1183	129.6 ± 17.1	802	129.5 ± 16.6	381	129.9 ± 18.2	0.661
DBP	1183	73.7 ± 11.0	802	74.5 ± 10.5	381	72.1 ± 11.7	< 0.0011
Hypertension	1183	781 (66.0)	802	561 (70.0)	381	220 (57.7)	< 0.0013
Hyperlipidemia	1183	734 (62.0)	802	547 (68.2)	381	187 (49.1)	< 0.0013
CKD	1183	89 (7.5)	802	37 (4.6)	381	52 (13.6)	< 0.0013
IBD type	1181		802		379		0.293
CD		29 (2.5)		18 (2.2)		11 (2.9)
UC		14 (1.2)		12 (1.5)		2 (0.53)
None		1138 (96.4)		772 (96.3)		366 (96.6)
IBD	1181	43 (3.6)	802	30 (3.7)	379	13 (3.4)	0.793
Stricturing disease	1183	17 (1.4)	802	10 (1.2)	381	7 (1.8)	0.433
DVT	1183	66 (5.6)	802	43 (5.4)	381	23 (6.0)	0.643

¹ANOVA.

²Kruskal-Wallis test.

³Pearson's χ² test. Statistics presented as mean ± SD or n (%). BMI: Body mass index; SBP: Systolic blood pressures; DBP: Diastolic blood pressures; CKD: Chronic kidney disease; CD: Crohn's disease; UC: Ulcerative colitis; IBD: Inflammatory bowel disease; DVT: Deep venous thrombosis.