Single-nucleotide polymorphisms based genetic risk score in the prediction of pancreatic cancer risk

Table 2 Characteristics of study population

Variables		Case, n = 254		Control, n = 1200		P value
Sex		n	%	n	%
	Male	156	64.42	748	62.23	0.831
	Female	98	38.58	452	37.67
Age at diagnosis, mean ± SD		63.31	10.01	48.80	15.49	0.00012
GRS, mean ± SD		1.96	3.84	1.09	0.94	< 0.00013
GRS: < 1		127	50.00	723	60.25	0.0021
GRS: 1-2		91	35.83	374	31.17
GRS: > 2		36	14.17	103	8.58
< 10th P		19	7.48	127	10.58	0.0071
10th-50th P		87	34.25	494	41.17
50th-90th P		111	43.70	471	39.25
90th P		37	14.57	108	9.00

¹Chi-square.

²t-test.

³Genetic risk score log transformed for t-test. GRS: Genetic risk score.