Diagnostic challenges in non-cirrhotic portal hypertension - porto sinusoidal vascular disease

doi:10.3748/wjg.v26.i22.3000

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 14, 2020; 26(22): 3000-3011
Published online Jun 14, 2020. doi: 10.3748/wjg.v26.i22.3000

Table 1 Histological differences between porto-sinusoidal vascular disease, extrahepatic portal vein obstruction and cirrhosis

	PSVD	EHPVO	Cirrhosis
Portal and periportal zone
Small portal vein obliteration (“hepato-portal sclerosis", phlebosclerosis)	++	+/-	-
Periportal shunt vessel	++	+	-
Fibrous septa	+/-; without bridging¹	-	++; with bridging delimitating nodules
Inflammation	-	-	++
Portal biliopathy	-	+/-	-
Liver lobule (parenchyma)
Perisinusoidal fibrosis	+	-	+/-
Sinusoidal dilatation	++	++	-
Nodular regenerative hyperplasia	+	+	-
Hepatocyte atrophy	+	+	-
Centrilobular zone
Central vein dilatation	++	+		-
Perivenular fibrosis	++	+		-

¹Incomplete septal fibrosis. ++: Almost always present; +: Usually present; +/–: Occasionally present; –: Usually absent; PSVD: Porto-sinusoidal vascular disease; EHPVO: Extrahepatic portal vein obstruction.

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Citation: Nicoară-Farcău O, Rusu I, Stefănescu H, Tanțău M, Badea RI, Procopeț B. Diagnostic challenges in non-cirrhotic portal hypertension - porto sinusoidal vascular disease. World J Gastroenterol 2020; 26(22): 3000-3011
URL: https://www.wjgnet.com/1007-9327/full/v26/i22/3000.htm
DOI: https://dx.doi.org/10.3748/wjg.v26.i22.3000

Nicoară-Farcău O, Rusu I, Stefănescu H, Tanțău M, Badea RI, Procopeț B. Diagnostic challenges in non-cirrhotic portal hypertension - porto sinusoidal vascular disease. World J Gastroenterol 2020; 26(22): 3000-3011 [PMID: 32587444 DOI: 10.3748/wjg.v26.i22.3000]

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