Retrospective Study
Copyright ©The Author(s) 2020.
World J Gastroenterol. May 14, 2020; 26(18): 2232-2246
Published online May 14, 2020. doi: 10.3748/wjg.v26.i18.2232
Table 7 Analysis of the risk factors associated with recurrence-free survival in patients who underwent total gastrectomy using the Cox proportional hazard model
Univariate
Multivariate
HR (95%CI)P valueHR (95%CI)P value
Age1.01 (1.00-1.02)0.0711.01 (1.00-1.02)0.032
Female sex1.23 (0.95-1.56)0.118
BMI0.96 (0.92-1.00)0.067
Tumor location
Upper 1/3Ref.
Mid 1/30.67 (0.51-0.87)0.002
Lower 1/30.86 (0.57-1.30)0.859
Tumor size1.11 (1.08-1.14)< 0.0011.03 (1.00-1.07)0.075
Borrmann type IV2.84 (2.10-3.83)< 0.0011.91 (1.32-2.76)0.001
CLN1.00 (0.99-1.01)0.612
T stage
T2Ref.Ref.
T32.20 (1.36-3.54)0.0011.31 (0.90-2.16)0.289
T44.18 (2.60-6.72)< 0.0011.90 (1.14-3.18)0.014
N stage
N0Ref.Ref.
N11.43 (0.89-2.31)0.1391.27 (0.77-2.07)0.348
N22.35 (1.55-3.56)< 0.0011.68 (1.06-2.65)0.026
N34.90 (3.43-6.99)< 0.0012.84 (1.87-4.32)< 0.001
Diffuse type histology1.14 (0.86-1.50)0.357
LVi2.41 (1.84-3.15)< 0.0011.44 (1.08-1.91)0.013
PNi1.71 (1.33-2.21)< 0.001
PRM (cm)
0-1.0Ref.
1.1-3.00.80 (0.55-1.15)0.225
3.1-5.00.63 (0.42-0.95)0.028
> 5.00.74 (0.51-1.07)0.104