Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn’s disease

Table 2 Odds ratios of genotypes and alleles of single nucleotide polymorphisms in the genes CLEC5A and NOD2

Gene	SNP	Genotype/allele	Odds ratio	95%CI1	P value1
CLEC5A	rs1285933	AA	1.90	1.18-3.05	0.009
		GG	0.84	0.50-1.42	0.516
		AG	0.65	0.42-1.01	0.054
		A	1.39	1.03-1.90	0.034
		G	0.72	0.53-0.97	0.034
NOD2	rs2066844 (SNP8)	TT	NA
		CC	0.31	0.14-0.67	0.003
		CT	3.00	1.36-6.60	0.006
		T	3.29	1.54-7.03	0.002
		C	0.30	0.14-0.65	0.002
NOD2	rs2066847 (SNP13)	CC-CC	NA
		C-C	0.51	0.26-1.02	0.056
		C-CC	1.47	0.72-2.98	0.287
		C	0.43	0.23-0.82	0.011
		CC	2.31	1.21-4.38	0.011

¹Unadjusted for multiple testing. SNP: Single nucleotide polymorphism; NA: Not applicable (missing in controls); CI: Confidence interval.