Iron metabolism imbalance at the time of listing increases overall and infectious mortality after liver transplantation

Table 3 Cox multiple regression analysis for overall mortality

Parameters	HR (95%CI)	P value
Hepatocellular carcinoma (yes/no)	1.58 (1.15; 2.16)	0.004
eGFR CKD EPI Cystatin C (mL/min)	0.99 (0.98; 0.99)	0.01
Cirrhosis aetiology (HCV as reference)		0.028
Alcohol	0.57 (0.39; 0.83)	0.003
Hepatitis B virus	0.50 (0.19; 1.28)	0.14
Other	0.66 (0.41; 1.08)	0.10
Transferrin saturation > 75%	1.73 (1.14; 2.63)	0.01
Ferritin (100-400 µg/L as reference)		0.009
< 100 µg/L	1.62 (1.12; 2.35)	0.01
> 400 µg/L	0.90 (0.59; 1.37)	0.63
Packed red blood cell (per unit)	1.05 (1.03; 1.08)	< 0.001

CI: Confidence interval; HCV: Hepatitis C virus; HR: Hazard ratio; ICU: Intensive care unit.