Mutation analysis of related genes in hamartoma polyp tissue of Peutz-Jeghers syndrome

Table 1 Clinicopathological data of enrolled patients with Peutz-Jeghers syndrome

Case No.	Onset time of pigment spots (yr)	Gender	Family history or not (detail)	Load of gastric polyps	Maximum diameter of gastric polyps (mm)	Load of duodenal and small intestinal polyps	Maximum diameter of duodenal and small intestinal polyps (mm)	Load of colorectal polyps	Maximum diameter of colorectal polyps (mm)	Number of hospitalization times	Number of operation times	Number of intervention times
1	0	Male	Yes (Father)	0	0	1-10	30	Unknown	Unknown	1	1	3
2	0	Male	No	1-10	10	31-40	80	11-20	70	3	1	4
3	7	Female	Yes (Father)	1-10	6	21-30	25	Unknown	Unknown	1	1	4
4	2	Male	No	11-20	17	1-10	25	1-10	40	1	1	4
5	10	Male	Yes (Son)	1-10	5	51-60	50	41-50	25	5	3	12
6	1	Male	Yes (Mother)	1-10	5	1-10	35	1-10	35	2	1	3
7	1	Male	No	1-10	23	1-10	50	Unknown	Unknown	1	0	2
8	1	Male	Yes (Grandmother and mother)	0	0	Unknown	Unknown	51-60	70	1	4	20
9	7	Male	Yes (Father)	0	0	11-20	60	21-30	12	1	1	9
10	13	Female	No	0	0	1-10	40	1-10	10	3	4	9
11	2	Male	No	1-10	8	1-10	25	1-10	6	2	0	4
12	0	Female	No	1-10	15	41-50	60	11-20	50	2	4	9
13	5	Female	Yes (Father and brother)	21-30	15	41-50	60	21-30	60	4	2	9
14	18	Female	No	21-30	5	11-20	30	1-10	6	2	1	5
15	0.8	Female	Yes (Father)	1-10	6	1-10	6	0	0	2	0	4
16	2	Male	Yes (Father)	21-30	20	31-40	45	51-60	45	2	7	21
17	4	Female	Yes (Son)	Unknown	Unknown	21-30	30	1-10	30	1	1	5
18	0	Male	No	1-10	15	Unknown	Unknown	1-10	20	1	0	2
19	5	Female	No	0	0	11-20	20	Unknown	Unknown	1	2	7
20	4	Female	Yes (Sister)	1-10	50	21-30	50	Unknown	Unknown	1	0	7