Systematic Reviews
Copyright ©The Author(s) 2019.
World J Gastroenterol. Mar 7, 2019; 25(9): 1142-1157
Published online Mar 7, 2019. doi: 10.3748/wjg.v25.i9.1142
Table 9 Individual studies included for induction of clinical remission in Crohn’s disease
StudyCountryInterventionComparatorStudy designFollow-upnInduction of clinical remission
Thomsen et al[45]Denmark, France, United Kingdom, Norway, Italy, Spain, Portugal, Greece, South Africa, Austria, Australia, and IrelandBudesonideMesalamineRCT8 wk18269% (budesonide) 45% (mesalamine) (P = 0.001)1
BudesonideMesalamineRCT16 wk18262% (budesonide) 36% (mesalamine) (P < 0.001)1
Pavez et al[41]ChileIFXAZARCT26 wk5080.44 (event rate IFX); 0.3 (event rate AZA)2