Copyright
©The Author(s) 2019.
World J Gastroenterol. Feb 28, 2019; 25(8): 923-940
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.923
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.923
Figure 5 Developing brain homeobox 2 activates the Shh-Gli1 signaling pathway in hepatocellular carcinoma.
A: Ectopic expression of developing brain homeobox 2 (Dbx2) upregulates the expression of Shh, PTCH1, PTCH2, SUFU, and GLI1 proteins, which are downregulated after Dbx2 knockdown; B: Proposed scheme of molecular basis for gain and loss of function of Dbx2 in HCC according to our results.
- Citation: Hu YT, Li BF, Zhang PJ, Wu D, Li YY, Li ZW, Shen L, Dong B, Gao J, Zhu X. Dbx2 exhibits a tumor-promoting function in hepatocellular carcinoma cell lines via regulating Shh-Gli1 signaling. World J Gastroenterol 2019; 25(8): 923-940
- URL: https://www.wjgnet.com/1007-9327/full/v25/i8/923.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i8.923