Triggers of histologically suspected drug-induced colitis

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Case Control Study

World J Gastroenterol. Feb 28, 2019; 25(8): 967-979
Published online Feb 28, 2019. doi: 10.3748/wjg.v25.i8.967

Table 5 Echocardiographic parameters n (%)

Parameter	Drug-induced colitis, n = 54 of 211 (25.6)	Non-inflammatory controls, n = 34 of 211 (16.1)	Inflammatory controls, n = 24 of 211 (11.4)
Dilated right atrium	4 (7.4)^a¹	4 (11.4)	5 (23.8)
Dilated left ventricle	8 (14.8)	0 (0.0)	6 (26.1)^b³
Hypokinesia	10 (18.5)	5 (14.3)	3 (13.0)
Right heart failure	5 (9.3)	4 (11.4)	2 (8.7)
Diastolic dysfunction	22 (43.1)	16 (48.5)	7 (30.4)
LV Function^b²,^b³
Normal (> 50%)	39 (72.2)	29 (85.3)	17 (73.9)
Slightly decreased (40%-50%)	4 (7.4)	5 (14.7)	1 (4.3)
Moderately decreased (30%-40%)	5 (9.3)	0 (0.0)	2 (8.7)
Severely decreased (< 30%)	6 (11.1)	0 (0.0)	3 (13.0)

¹Drug-induced colitis vs inflammatory controls.

²Drug-induced colitis vs non-inflammatory controls.

³Non-inflammatory controls vs inflammatory controls.

^aP < 0.05.

^bP < 0.01.

Statistical analysis was carried out with χ² test. LV : Left ventricular.

Citation: Brechmann T, Günther K, Neid M, Schmiegel W, Tannapfel A. Triggers of histologically suspected drug-induced colitis. World J Gastroenterol 2019; 25(8): 967-979
URL: https://www.wjgnet.com/1007-9327/full/v25/i8/967.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i8.967

Brechmann T, Günther K, Neid M, Schmiegel W, Tannapfel A. Triggers of histologically suspected drug-induced colitis. World J Gastroenterol 2019; 25(8): 967-979 [PMID: 30833802 DOI: 10.3748/wjg.v25.i8.967]

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