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Copyright ©The Author(s) 2019.
World J Gastroenterol. Feb 7, 2019; 25(5): 539-551
Published online Feb 7, 2019. doi: 10.3748/wjg.v25.i5.539
Table 1 Comparison of physiological actions of acyl- and des-acyl ghrelin
ParameterAcyl-ghrelinDes-acyl ghrelinRef.
Appetite1IncreaseDecrease[87]
Metabolism1Positive energy balanceNegative energy balance[87]
AdipogenesisIncreaseIncrease[88]
Cardiomyocyte and endothelial cell deathInhibitionInhibition[20]
Papillary muscle contractilityNegative inotropyNegative inotropy[89]
Blood pressureDecreaseDecrease[90]
Insulin release1DecreaseIncrease[91]
Insulin sensitivity1DecreaseIncrease[92]
Muscle wastingDecreaseDecrease[93]
Gastric emptying1IncreaseDecrease[94]
Gastric motility1IncreaseDecrease[95]