Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA

doi:10.3748/wjg.v25.i48.6939

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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Prospective Study

World J Gastroenterol. Dec 28, 2019; 25(48): 6939-6948
Published online Dec 28, 2019. doi: 10.3748/wjg.v25.i48.6939

Table 2 Clinical patient data

Characteristics		Value
Number of patients		47
Age	mean, range (yr)	63.6 ± 12.3, 32-87
Gender	Female/male	16/31
Localization of primary	Rectum	13
	Colon	14
	Rectosigmoid	8
	Sigmoid	7
	Cecum	3
	Others	2
Localization of metastasis	Liver only	35
	Liver and/or other	12
Surgical treatment
Number of surgeries¹		63
Synchronous mCRC	Combined (primary and liver)	12
	Primary before metastases	8
	Liver first	2
	Liver in the second stage	14
Metachronous mCRC	Liver	24
	Other metastases	3
Radicality	R0	40
	R1	7
	R2	16
Recurrence (R0 surgeries)	Number²	27
	Mean time to reccurence, range (mo)	9.0 ± 5.1, 3-22

¹Postoperative ctDNA was available for 50 surgeries.

²All parameters for recurrence evaluation were available for 22 R0 surgeries. mCRC: Metastatic colorectal cancer; R0: Complete resection; R1: Microscopically incomplete resection; R2: Macroscopically incomplete resection.

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Citation: Benešová L, Hálková T, Ptáčková R, Semyakina A, Menclová K, Pudil J, Ryska M, Levý M, Šimša J, Pazdírek F, Hoch J, Blaha M, Minárik M. Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA. World J Gastroenterol 2019; 25(48): 6939-6948
URL: https://www.wjgnet.com/1007-9327/full/v25/i48/6939.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i48.6939

Benešová L, Hálková T, Ptáčková R, Semyakina A, Menclová K, Pudil J, Ryska M, Levý M, Šimša J, Pazdírek F, Hoch J, Blaha M, Minárik M. Significance of postoperative follow-up of patients with metastatic colorectal cancer using circulating tumor DNA. World J Gastroenterol 2019; 25(48): 6939-6948 [PMID: 31908397 DOI: 10.3748/wjg.v25.i48.6939]

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