Irisin attenuates intestinal injury, oxidative and endoplasmic reticulum stress in mice with L-arginine-induced acute pancreatitis

Figure 3 Irisin administration alleviates intestinal apoptosis in experimental acute pancreatitis. A: Representative photos of TUNEL staining (green) and corresponding nuclear counterstaining (blue) in the intestines; B: Quantitative analysis of TUNEL-positive cells; C-E: Western blot analysis of the expression of BAX, caspase-3 and cleaved caspase-3 in the intestines. n = 6, mean ± standard error of mean; ^aP < 0.05 vs sham group; ^cP < 0.05 vs vehicle group. AP: Acute pancreatitis; TUNEL: TdT-mediated dUTP nick-end labeling.