Long noncoding RNA NALT1-induced gastric cancer invasion and metastasis via NOTCH signaling pathway

Table 1 Patients characteristics and univariate analysis, n = 336

Characteristics	n (%)	DFS			OS
		Mo	P value	F	Mo	P value	F
Age, median, yr			0.280	1.172		0.641	0.218
≥ 60	178	37.73			44.80
< 60	158	40.77			45.95
Gender			0.085	2.982		0.216	1.537
Male	236 (70.2)	37.59			44.35
Female	100 (29.8)	42.86			47.68
Bormann type			0.000	55.616		0.000	49.755
I	25	64.00			64.00
II	147	45.92			51.50
III	159	29.62			37.20
IV	5	19.60			29.80
Tumor size			0.000	26.829		0.000	20.674
≥ 5 cm	142	30.99			38.99
< 5 cm	194	45.13			49.99
Location			0.142	3.899		0.325	2.247
Up	75	34.15			41.80
Middle	90	42.04			47.60
Low	171	39.84			45.70
Tumor histological morphology			0.788	0.476		0.870	0.277
Adenocarcinoma	260	39.30			45.33
Mixed carcinoma	75	38.35			45.13
Absolute signet ring cell carcinoma	1	35.00			45.00
Lauren type			0.298	2.420		0.309	2.349
Intestinal	156	38.79			44.88
Mixed carcinoma	75	35.15			41.99
Diffuse	105	42.57			48.42
Tumor differentiation			0.000	20.700		0.000	17.649
Moderate and high	167	45.38			50.41
Poor	169	33.01			40.33
Vessel invasion			0.000	19.213		0.000	15.243
Yes	98	29.85			37.40
No	238	42.99			48.61
Perineural invasion			0.000	17.809		0.000	16.686
Yes	84	28.45			36.83
No	252	42.73			48.17
T category			0.000	105.672		0.000	91.002
T1	60	65.95			65.98
T2	22	58.82			61.32
T3	12	60.25			62.00
T4	242	29.68			37.94
N category			0.000	232.168		0.000	217.417
N0	139	62.74			63.47
N1	58	36.12			48.07
N2	65	23.88			33.55
N3	74	10.66			18.16
TNM stage			0.000	218.328		0.000	204.741
I	69	64.52			64.55
II	81	63.59			66.40
III	14	19.26			29.27
IV	2	5.00			8.50
NALT1			0.000	20.645		0.000	18.035
Weak-expression	159	45.24			50.30
Over-expression	177	33.69			40.88

DFS: Disease-free survival; OS: Overall survival.