MicroRNA-30c inhibits pancreatic cancer cell proliferation by targeting twinfilin 1 and indicates a poor prognosis

Figure 4 Overexpression of miR-30c inhibits tumor growth in vivo. A: Images of the xenograft model from each treated group. B: Tumor growth curves of each treated group in mice (n = 5) inoculated with the indicated cells on the indicated days. C: Tumor weight of each treated group. D: H&E staining and immunohistochemistry analysis of Ki-67 and twinfilin 1 (TWF1) in each treated group. Scale bar, 50 μm (red line). E and F: Quantitative real-time polymerase chain reaction analysis of miR-30c and TWF1 expression in xenograft tumors of the indicated group. The data are presented as the mean ± standard deviation. P < 0.05 was considered statistically significant. ^eP < 0.001 vs control group. TWF1: Twinfilin 1.