Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis

Figure 8 Trial sequential analysis of the healing rates of peptic ulcers. Trial sequential analysis of the healing rates showed that an information size of 635 participants was required. Cumulative Z-curve crossed the trial sequential monitoring boundary, showing significant evidence of eradication rates. The cumulative values of the Z scores crossed conventional boundary values, trial sequential monitoring boundaries, and RIS line, suggesting that the trials were sufficient, and no alterations of the conclusions were likely.