Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis

doi:10.3748/wjg.v25.i39.6025

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World Journal of Gastroenterology

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1007-9327

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Meta-Analysis

World J Gastroenterol. Oct 21, 2019; 25(39): 6025-6040
Published online Oct 21, 2019. doi: 10.3748/wjg.v25.i39.6025

Table 3 Subgroup analyses of eradication rates

Comparison	Eradication rate (%)		Heterogeneity		OR	95%CI	P value
Comparison	Allicin group	Control	I² (%)	P value	OR	95%CI	P value
Allicin + PTT vs PTT[15-20] (ITT)	92.47	82.61	0	0.975	2.87	1.65-4.99	< 0.001
Allicin + PTT vs PTT[15-20] (PP)	92.81	82.91	0	0.984	2.66	1.53-4.64	0.001
Allicin-PPI-B-T-C vs PPI-B-T-C[21,22] (ITT/PP)	94.87	85.25	0	0.764	3.19	1.38-7.38	0.007
Allicin-PPI-Am-F vs PPI-Am-F[15,18,20] (ITT/PP)	92.46	81.33	0	0.986	2.38	0.99-5.71	0.053

PPI: Proton pump inhibitor; PTT: Proton pump inhibitor triple therapy; Am: Amoxicillin; F: Furazolidone; C: Clarithromycin; T: Tinidazole; B: Bismuth potassium citrate tablets; ITT: Intent-to-treat analysis; PP: Pre-protocol analysis; OR: Odds ratio; CI: Confidence interval.

Citation: Si XB, Zhang XM, Wang S, Lan Y, Zhang S, Huo LY. Allicin as add-on therapy for Helicobacter pylori infection: A systematic review and meta-analysis. World J Gastroenterol 2019; 25(39): 6025-6040
URL: https://www.wjgnet.com/1007-9327/full/v25/i39/6025.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i39.6025