Association of XPG rs2094258 polymorphism with gastric cancer prognosis

Table 2 Single nucleotide polymorphism and genotype distribution between gastric cancer cases and controls

SNP	Genotype	Case	Control	HWE	P-value	OR	95%CI	P-value	OR1	95%CI	P-value
		n = 956	n = 1012
Rs2094258	CC	390 (40.8)	437 (43.2)	0.318	0.853	1.00
	CT	441 (46.1)	464 (45.8)			1.07	0.88-1.29	0.545	1.05	0.86-1.31	0.626
	TT	125 (13.1)	111 (11.0)			1.26	0.94-1.69	0.133	1.19	0.90-1.20	0.249
	Dominant	566 (59.2)	575 (56.8)			1.10	0.92-1.32	0.284	1.06	0.87-1.37	0.388
	Recessive	831 (86.9)	901 (89.0)			1.22	0.93-1.60	0.150	1.19	0.91-1.72	0.303
Rs751402	CC	366 (38.3)	371 (36.7)	0.183	0.913	1.00
	CT	467 (48.8)	476 (47.0)			0.95	0.78-1.16	0.618	0.98	0.77-1.33	0.774
	TT	123 (12.9)	165 (16.3)			0.88	0.67-1.15	0.341	0.90	0.61-1.28	0.491
	Dominant	590 (61.7)	632 (62.5)			0.95	0.79-1.14	0.554	0.95	0.78-1.22	0.711
	Recessive	833 (87.1)	847 (83.7)			0.90	0.71-1.15	0.411	0.93	0.69-1.18	0.487
Rs2296147	TT	599 (62.7)	640 (63.2)	0.076	0.963	1.00
	CT	301 (31.5)	332 (32.9)			0.97	0.80-1.17	0.745	0.97	0.80-1.19	0.674
	CC	56 (5.9)	40 (3.9)			1.50	0.98-2.28	0.059	1.40	0.97-2.50	0.061
	Dominant	357 (37.3)	372 (36.8)			1.03	0.85-1.23	0.789	1.01	0.80-1.38	0.865
	Recessive	900 (94.1)	973 (96.1)			1.51	1.00-2.29	0.050	1.36	0.99-2.49	0.053
Rs1047768	TT	505 (52.8)	540 (53.4)	0.367	0.832	1.00
	CT	379 (39.6)	406 (40.1)			1.00	0.83-1.20	0.985	1.00	0.80-1.28	0.989
	CC	72 (7.6)	66 (6.5)			1.17	0.82-1.66	0.395	1.11	0.79-1.92	0.505
	Dominant	451 (47.2)	472 (46.6)			1.02	0.86-1.22	0.812	1.01	0.81-1.45	0.897
	Recessive	884 (92.5)	946 (93.5)			1.17	0.83-1.65	0.381	1.12	0.74-1.84	0.561
Rs873601	GG	271 (28.3)	288 (28.5)	0.247	0.884	1.00
	AG	475 (49.7)	514 (50.8)			0.98	0.80-1.21	0.865	0.99	0.63-1.88	0.931
	AA	210 (22.0)	210 (20.7)			1.06	0.83-1.37	0.638	1.03	0.71-2.01	0.807
	Dominant	685 (71.7)	724 (71.5)			1.12	0.92-1.37	0.245	1.07	0.82-1.94	0.466
	Recessive	746 (78.0)	802 (79.2)			1.08	0.87-1.33	0.511	0.98	0.88-1.37	0.685

¹OR was calculated by Logistic regression method after adjusting for age and gender. H. pylori: Helicobacter pylori infection status; SNP: Single nucleotide polymorphism; HWE: Hardy-Weinberg equilibrium; OR: Odds ratio.