Basic Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Sep 7, 2019; 25(33): 4904-4920
Published online Sep 7, 2019. doi: 10.3748/wjg.v25.i33.4904
Figure 1
Figure 1 Metabolic parameters in ob/ob mice fed amylin liver non-alcoholic steatohepatitis (AMLN) or Gubra amylin non-alcoholic steatohepatitis (GAN) diet for 8-16 wk. A: Body weight; B: Body composition; C: Terminal liver weight (week 16); D: An intraperitoneal glucose tolerance test (ipGTT) was performed in week 7 of the feeding period, glucose excursion curves; E: Glucose area under the curve (AUC, 0-180 min); F: Plasma insulin (0, 15, 30 min). aP < 0.05, bP < 0.01, cP < 0.001 vs chow-fed C57BL/6J (Chow C57) controls; dP < 0.001 vs amylin liver non-alcoholic steatohepatitis (AMLN) diet (n = 5-6 mice per group). AMLN: Amylin liver non-alcoholic steatohepatitis diet; GAN: Gubra amylin non-alcoholic steatohepatitis diet; iPGTT: Intraperitoneal glucose tolerance test.

  • Citation: Boland ML, Oró D, Tølbøl KS, Thrane ST, Nielsen JC, Cohen TS, Tabor DE, Fernandes F, Tovchigrechko A, Veidal SS, Warrener P, Sellman BR, Jelsing J, Feigh M, Vrang N, Trevaskis JL, Hansen HH. Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source. World J Gastroenterol 2019; 25(33): 4904-4920
  • URL: https://www.wjgnet.com/1007-9327/full/v25/i33/4904.htm
  • DOI: https://dx.doi.org/10.3748/wjg.v25.i33.4904