Review of current diagnostic methods and advances in Helicobacter pylori diagnostics in the era of next generation sequencing

Table 2 Standard clarithromycin-based triple regimens using metronidazole or amoxicillin and associated costs

	Drug	Dose	Costs (EUR) per dose	Costs (EUR) for 7 d	Costs (EUR) for 14 d
Standard triple regimen (with metronidazole)	Clarithromycin	500 mg (twice daily)	1.1	15.4	30.8
	Metronidazole	500 mg (three times daily)	0.6	13.1	26.2
	Pantoprazole (Proton-pump inhibitor)	Standard dose (twice daily)	0.1	1.6	3.2
In total			1.8	30.1	60.2
Standard triple regimen (with amoxicillin)	Clarithromycin	500 mg (twice daily)	1.1	15.4	30.8
	Amoxicillin	1 g (twice daily)	1.4	20.2	40.4
	Pantoprazole (Proton-pump inhibitor)	Standard dose (twice daily)	0.1	1.6	3.2
In total			2.6	37.2	74.4