Overview and comparison of guidelines for management of pancreatic cystic neoplasms

Table 1 Variables considered in the initial evaluation of pancreatic cystic neoplasms

		European	ACG	AGA	IAP	ACR
Symptoms	Jaundice	AI	HR	HR	HR	HR
	Pancreatitis	RI	HR		WF
Imaging based cyst characteristics	Main pancreatic duct dilation	> 10 mm AI 5-10 mm RI	> 5 mm HR	HR	> 10 mm HR 5-10 mm WF	> 10 mm HR 7-10 mm WF
	Associated mass		HR	HR	HR	HR
	Mural nodule	> 5 mm AI < 5 mm RI	HR	HR	> 5 mm HR < 5 mm WF	WF
	Cyst size	≥ 4 cm RI	≥ 3 cm HR		> 3 cm WF	> 3 cm WF
	Parenchymal atrophy				WF
	Lymphadenopathy				WF
Serum based	CA19-9	RI	HR		WF
	New onset diabetes	RI

AI: Absolute indication; RI: Relative indication; HR: High risk; WF: Worrisome features.