©The Author(s) 2019.
World J Gastroenterol. Aug 7, 2019; 25(29): 4007-4018
Published online Aug 7, 2019. doi: 10.3748/wjg.v25.i29.4007
Published online Aug 7, 2019. doi: 10.3748/wjg.v25.i29.4007
Table 5 Curative treatments for dermatological toxicities (Primary analysis set, n = 229)
| Day 15 (n = 214) | Month 1 (n = 208) | Month 2 (n = 186) | Month 3 (n = 153) | Month 4 (n = 122) | Month 5 (n = 93) | Month 6 (n = 87) | |
| At least one curative treatment, n (%) | 117/214 (54.7) | 124/208 (59.6) | 118/186 (63.4) | 92/153 (60.1) | 63/120 (52.5) | 47/92 (51.1) | 39/87 (44.8) |
| Emollients | 74 (63.2) | 82 (66.1) | 84 (71.2) | 69 (75.0) | 45 (71.4) | 29 (61.7) | 24 (61.5) |
| Oral antibiotics | 88 (75.2) | 90 (72.6) | 88 (74.6) | 65 (70.7) | 43 (68.3) | 31 (66.0) | 28 (71.8) |
| Emollients and oral antibiotics | 60 (51.3) | 61 (49.2) | 61 (51.7) | 47 (51.1) | 28 (44.4) | 17 (36.2) | 16 (41.0) |
| Antiseptics | 9 (7.8) | 7 (5.6) | 11 (9.3) | 7 (7.6) | 2 (3.2) | 1 (2.1) | 0 (0.0) |
| Antihistamines | 12 (10.3) | 10 (8.1) | 11 (9.4) | 10 (10.9) | 6 (9.5) | 5 (10.6) | 2 (5.1) |
| Corticosteroids | 19 (16.2) | 26 (21.0) | 23 (19.5) | 19 (20.7) | 12 (19.0) | 6 (12.8) | 9 (23.1) |
| Other (including topical antibiotics) | 51 (44.0) | 47 (37.9) | 35 (29.7) | 29 (31.9) | 20 (31.7) | 16 (34.0) | 13 (33.3) |
| Topical antibiotics | 48 (94.1) | 43 (91.5) | 30 (85.7) | 25 (86.2) | 18 (90.0) | 16 (100) | 13 (100) |
- Citation: Bouché O, Ben Abdelghani M, Labourey JL, Triby S, Bensadoun RJ, Jouary T, Des Guetz G. Management of skin toxicities during panitumumab treatment in metastatic colorectal cancer. World J Gastroenterol 2019; 25(29): 4007-4018
- URL: https://www.wjgnet.com/1007-9327/full/v25/i29/4007.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i29.4007