Surgical techniques and postoperative management to prevent postoperative pancreatic fistula after pancreatic surgery

Table 2 Characteristics and intraoperative data of 7 randomized controlled trials included studies comparing invagination vs duct-to-mucosa

		Pubricat-ion	Sample		Pancreatic parenchyma (soft/ hard)		stents		Use of smatostatin analogs
First author	Country	year	D to M	Inv	D to M	Inv	D to M	Inv	D to M	Inv	Result
Peng et al[56]	China	2007	111	106	39/72	37/69	NA	No	No	No	Invagina-tion significan-tly reduced POPF
Berger et al[57]	United States	2008	97	100	50/47	51/49	Intraoper-ative temporary	No	No	No	Invaginat-ion significan-tly reduced POPF
Senda et al[58]	Japan	2018	61	59	31/30	30/29	Yes	Yes	NA	NA	NS
Bai et al[59]	China	2016	64	68	36/28	44/24	47 used	52 used	2 used	12 used	D to M significan-tly reduced POPF
El Nakeeb et al[60]	Egypt	2018	53	54	25/28	27/27	Intraoper-ative temporary	Intraoper-ative temporary	NA	NA	NS
Singh et al[61]	India	2017	97	96	42/55	48/48	15 used	26 used	38 used	31 used	NS
Maggiori et al[62]	France	2010	25	22	11/14	10/12	NA	NA	11 used	10 used	NS

D to M: Duct to mucosa; Inv: Invagination; NA: Not available; NS: Not significant.