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©The Author(s) 2019.
World J Gastroenterol. Jun 28, 2019; 25(24): 3069-3078
Published online Jun 28, 2019. doi: 10.3748/wjg.v25.i24.3069
Published online Jun 28, 2019. doi: 10.3748/wjg.v25.i24.3069
Table 1 Patient characteristics
| Young (≤ 50 yr) | Old (> 50 yr) | P value | |
| (n = 45) | (n = 405) | ||
| Sex (male) | 39/45 (87%) | 342/405 (84%) | 0.86 |
| Ethnicity (white) | 43/44 (98%) | 377/387 (97%) | 0.70 |
| BMI, kg/m2 (mean ± SD) | 29.69 ± 6.05 | 28.53 ± 5.72 | 0.09 |
| BMI > 30 kg/m2 | 21/44 (48%) | 124/389 (32%) | 0.04 |
| Diabetes | 5/45 (11%) | 91/390 (23%) | 0.01 |
| Hypertension | 13/45 (29%) | 211/382 (55%) | < 0.001 |
| Family history of malignancy | 21/44 (48%) | 234/382 (61%) | 0.08 |
| Family history of esophageal adenocarcinoma | 1/44 (2%) | 17/382 (5%) | 0.78 |
| GERD symptoms | 24/44 (55%) | 148/386 (38%) | 0.04 |
| Smoking | |||
| Ever smoking | 25/44 (57%) | 297/393 (76%) | 0.01 |
| Current smoking | 4/44 (9%) | 47/392 (11%) | 0.75 |
| Pack-years (mean ± SD) | 13.97 ± 15.56 | 23.46 ± 27.21 | 0.02 |
| Alcohol | |||
| Ever alcohol | 37/45 (82%) | 297/387 (77%) | 0.52 |
| Current alcohol | 31/45 (69%) | 241/375 (64%) | 0.54 |
| Medication use | |||
| Proton pump inhibitors | 38/43 (88%) | 335/374 (90%) | 0.98 |
| Low-dose aspirin | 5/45 (11%) | 130/388 (34%) | < 0.01 |
| NSAIDs | 4/45 (9%) | 34/384 (9%) | 0.79 |
| Statins | 10/45 (22%) | 189/388 (49%) | < 0.001 |
| Endoscopy | |||
| Prague C, median (IQR), cm | 2 (0-5) | 1 (0-5) | 0.52 |
| Prague M, median (IQR), cm | 4 (2-7) | 4 (2-7) | 0.43 |
| Hiatus hernia | 35/45 (78%) | 350/405 (86%) | 0.12 |
- Citation: Iwaya Y, Shimamura Y, Goda K, Rodríguez de Santiago E, Coneys JG, Mosko JD, Kandel G, Kortan P, May G, Marcon N, Teshima C. Clinical characteristics of young patients with early Barrett’s neoplasia. World J Gastroenterol 2019; 25(24): 3069-3078
- URL: https://www.wjgnet.com/1007-9327/full/v25/i24/3069.htm
- DOI: https://dx.doi.org/10.3748/wjg.v25.i24.3069