Role of epigenetics in transformation of inflammation into colorectal cancer

doi:10.3748/wjg.v25.i23.2863

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2019; 25(23): 2863-2877
Published online Jun 21, 2019. doi: 10.3748/wjg.v25.i23.2863

Table 2 LncRNAs regulate the inflammation-cancer transformation

LncRNA	Target genes	Functions in CRC
PRINS	miR-491-5p/PMAIP1/TFF3	Inhibited apoptosis
FEZF1-AS1	PKM2/STAT3	Accelerated CRC occurrence
AB073614	JAK/STAT3	Induced EMT
HOTAIR	MiR-218/EZH2/NF-kB	Chemotherapeutic resistance

CRC: Colorectal cancer; EMT: Epithelial-mesenchymal transition.

Citation: Yang ZH, Dang YQ, Ji G. Role of epigenetics in transformation of inflammation into colorectal cancer. World J Gastroenterol 2019; 25(23): 2863-2877
URL: https://www.wjgnet.com/1007-9327/full/v25/i23/2863.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i23.2863