Sp1 contributes to overexpression of stanniocalcin 2 through regulation of promoter activity in colon adenocarcinoma

Figure 1 STC2 was overexpressed in colon tumor tissues and contributed to cancer development. A: The relative transcript expression of STC2 was conducted with normal (adjacent colorectal tissues, 41 cases) and colon tumor tissues (286 cases). b), ^cP < 0.001 vs normal; B: The relative transcript expression of STC2 was evaluated in 274 cases colon tumor tissues with different disease condition, ^aP < 0.05 vs normal group, ^cP < 0.001 vs normal group; C: With RNA-seq analysis of STC2 expression in primary colon cancer and liver metastatic colon cancer tissues of stage IV patients (GSE50760). Subset 1: Primary colon cancer; Subset 2: Colon cancer with liver metastasis. STC2: Stanniocalcin 2; FPKM: Fragments per kilobase million.