Brucea javanica oil emulsion improves the effect of radiotherapy on esophageal cancer cells by inhibiting cyclin D1-CDK4/6 axis

Figure 3 The promotion of the apoptotic rate of esophageal carcinoma cells during radiotherapy in combination with Brucea javanica oil emulsion. A: The viability of EC109 and JAR treaded with BJOE and radiotherapy; B: The values of EC50 and LC50 of EC109 and JAR; C: Clonogenic assays using radiotherapy in combination with BJOE (C) and cell apoptotic detection (D). In all the above, at least three repeats were carried out, and the mean ± SD is presented, ^aP < 0.05; ^bP < 0.01. BJOE: Brucea javanica oil emulsion; SD: Standard deviation; EC50: Half-maximal effective concentration; LC50: Half-maximal lethal concentration.