Novel abdominal negative pressure lavage-drainage system for anastomotic leakage after R0 resection for gastric cancer

Table 4 Risk factors predictive of failure-to-rescue after anastomotic leakage with radical gastrectomy for gastric cancer

Factor	Univariate analysis
	OR (95%CI)	P-value
ANPLDS therapy
No	Reference	0.040
Yes	0.103 (0.012-0.898)
Age, yr
< 65	Reference	0.532
≥ 65	0.607 (0.127-2.900)
Sex
Female	Reference	0.998
Male	/
BMI, kg/m2
< 25	Reference	0.773
≥ 25	1.289 (0.230-7.219)
History of abdominal surgery
No	Reference	0.849
Yes	0.808 (0.090-7.286)
Tumor site
Upper	Reference	0.935
Middle	/	0.998
Lower	0.697 (0.106-4.578)	0.707
≥ 2 areas	1.394 (0.203-9.585)	0.736
Malnourished
No	Reference	0.710
Yes	1.388 (0.247-7.802)
Tumor size, cm
≤ 5	Reference	0.700
> 5	1.361 (0.283-6.535)
AJCC-TNM stage, 8th edition
I-II	Reference	0.115
III	5.692 (0.654-49.570)
Comorbidities
No	Reference	0.448
Yes	1.833 (0.383-8.765)
HB, g/dL
≥ 90	Reference	0.728
< 90	0.678 (0.076-6.063)
ASA
I-II	Reference	0.567
III-IV	1.944 (0.200-18.920)
Operation method
Open	Reference	0.073
Laparoscopic	0.226 (0.044-1.149)
Type of resection
Subtotal gastrectomy	Reference	0.763
Total gastrectomy	1.300 (0.236-7.166)
Type of reconstruction
Billroth I	Reference	0.997
Billroth II	0.817 (0.148-4.520)	0.817
Roux-en-Y	/	> 0.999
Other	/	0.999
Surgical duration, min (SD)
> 180	Reference	0.138
≤ 180	3.629 (0.661-19.914)
Intraoperative blood loss, ml
> 50	Reference	0.997
≤ 50	/

ANPLDS: Abdominal negative pressure lavage-drainage system; BMI: Body mass index; HB: Hemoglobin; ASA: American Society of Anesthesiologists.