Basic Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Jan 14, 2019; 25(2): 220-232
Published online Jan 14, 2019. doi: 10.3748/wjg.v25.i2.220
Table 1 Stratified analysis of recurrence-free survival in The Cancer Genome Atlas cohort
CharacteristicRecurrence-free survival
High-risk/low-riskHR (95%CI)P-value
Overall165/1691.807 (1.329-2.457)< 0.001a
TNM stage
I/II104/1301.595 (1.071-2.375)0.018a
III/IV48/291.295 (0.759-2.208)0.340
Gender
Male111/1162.150 (1.476-3.133)< 0.001a
Female53/540.940 (0.552-1.598)0.818
Age (yr)
≤ 6081/802.244 (1.435-3.510)< 0.001a
> 6083/901.155 (0.758-1.761)0.499
Hepatitis B
With HBV39/602.013 (1.056-3.837)0.022a
Without HBV46/321.371 (0.685-2.743)0.371
Hepatitis C
With HCV26/250.964 (0.466-1.997)0.922
Without HCV46/541.434 (0.792-2.596)0.224
Alcohol consumption
Yes55/522.209 (1.301-3.752)0.002a
No107/1101.404 (0.954-2.066)0.080
Liver cirrhosis
Yes27/481.353 (0.697-2.626)0.340
No62/631.263 (0.770-2.070)0.354
Albumin (g/dL)
≤ 3.536/410.908 (0.464-1.776)0.776
> 3.588/1101.682 (1.132-2.501)0.007a
Creatinine (mg/dL)
< 1.185/1011.419 (0.945-2.130)0.084
≥ 1.139/501.686 (0.891-3.189)0.088
Alpha-fetoprotein (ng/mL)
≤ 2055/840.874 (0.535-1.428)0.590
> 2058/581.780 (1.066-2.972)0.021a
Platelet(× 109/L)
≤ 25080/1021.517 (0.983-2.340)0.052
> 25045/521.431 (0.818-2.502)0.181
Race
Asian73/752.160 (1.329-3.510)0.001a
White78/821.275 (0.847-1.919)0.238
BMI
< 2475/711.597 (1.007-2.533)0.039a
≥ 2475/861.692 (1.085-2.638)0.017a
Family history
Yes45/551.883 (1.074-3.304)0.022a
No102/891.367 (0.919-2.034)0.120
ECOG
064/882.106 (1.279-3.468)0.002a
> 061/531.334 (0.837-2.125)0.223