Meta-Analysis
Copyright ©The Author(s) 2019.
World J Gastroenterol. May 21, 2019; 25(19): 2383-2401
Published online May 21, 2019. doi: 10.3748/wjg.v25.i19.2383
Table 7 Diagnostic accuracy parameters for advanced neoplasia detection based on quantitative faecal immunochemical test for haemoglobin threshold concentration and brand
BrandThreshold(µg/g faeces)Author, yearSensitivity1Specificity1
Mixed cohorts
OC-Sensor®5Ou, 2013[21]56.8 (39.5-72.9)88.7 (85.7-91.2)
OC-Sensor®25Rozen, 2010[17]27.5 (20.3-34.7)96.7 (95.8-97.6)
OC-Sensor®25Terhaar sive Droste, 2010[32]48.3 (42.6-53.9)94.3 (93.2-95.3)
OC-Sensor®30Rozen, 2010[17]26.8 (19.9-34.7)97.3 (96.5-98.1)
OC-Sensor®30Terhaar sive Droste, 2010[32]46.0 (40.4-51.7)95.1 (94.1-96.1)
OC-Sensor®40Rozen, 2010[17]26.2 (19.1-33.2)97.8 (97.0-98.5)
OC-Sensor®40Terhaar sive Droste, 2010[32]43.2 (37.6-48.9)95.8 (94.8-96.7)
HM-JACKarc®LoDAuge, 2016[22]96.6 (82.8-93.4)10.6 (6.9-15.9)
HM-JACKarc®10Auge, 2016[22]34.5 (19.9-52.7)87.2 (81.6-91.3)
HM-JACKarc®20Auge, 2016[22]31.0 (17.3-49.2)92.8 (88.0-95.7)
HM-JACKarc®30Auge, 2016[22]31.0 (17.3-49.2)93.3 (88.7-96.1)
HM-JACKarc®40Auge, 2016[22]27.6 (14.7-45.7)93.9 (89.4-96.6)
FOB Gold®10Auge, 2018[30]45.7 (33.7-58.1)84.7 (80.8-88.0)
FOB Gold®20Auge, 2018[30]37.1 (26.1-49.6)87.9 (84.2-90.8)
FOB Gold®30Auge, 2018[30]35.7 (24.6-48.1)90.3 (87.0-93.1)
FOB Gold®40Auge, 2018[30]32.9 (22.4-45.2)91.1 (87.8-93.6)
FOB Gold®50Auge, 2018[30]31.4 (20.9-43.6)92.3 (89.3-94.7)
FOB Gold®60Auge, 2018[30]30.0 (19.9-42.3)92.3 (89.2-94.6)
100% symptomatic
HM-JACK®20Parente, 2012[24]35.6 (27.9-44.1)94.5 (89.7-97.2)