Role of D2 gastrectomy in gastric cancer with clinical para-aortic lymph node metastasis

Table 4 Demographic characteristics and response of para-aortic nodes

Variable	n	Response of PAN		P-value	Treatment		P-value
		Complete response	Residual tumor		With D2 resection	Without D2 resection
Tumor location				0.5647			0.0931
Upper	21	10 (41.7)	11 (45.8)		7 (31.8)	14 (53.8)
Middle	21	12 (50.0)	9 (37.5)		10 (45.5)	11 (42.3)
Lower	6	2 (8.3)	4 (16.7)		5 (22.7)	1 (3.8)
Clinical tumor stage				0.5510			0.4545
T3	3	2 (8.3)	1 (4.2)		2 (9.1)	1 (3.8)
T4	45	22 (91.7)	23 (95.8)		20 (90.9)	25 (96.2)
Clinical nodal stage				0.2673			0.1640
N0-1	9	6 (25.0)	3 (12.5)		6 (27.3)	3 (11.5)
N2-3	39	18 (75.0)	21 (87.5)		16 (72.7)	23 (88.5)
Macroscopic type				0.2199			0.5158
1-3 or 5	41	22 (91.7)	19 (79.2)		18 (81.8)	23 (88.5)
4	7	2 (8.3)	5 (20.8)		4 (18.2)	3 (11.5)
No. of PAN stations involved				0.1044			0.0012
1-2	35	20 (83.3)	15 (62.5)		21 (95.5)	14 (53.8)
3-4	13	4 (16.7)	9 (37.5)		1 (4.5)	12 (46.2)
Largest PAN in short-axis				0.0822			0.0899
< 10 mm	22	14 (58.3)	8 (33.3)		13 (59.1)	9 (34.6)
≥ 10 mm	26	10 (41.7)	16 (66.7)		9 (40.9)	17 (65.4)
Largest PAN in short-axis				0.0455			0.0026
< 15 mm	36	21 (87.5)	15 (62.5)		21 (95.5)	15 (57.7)
≥ 15 mm	12	3 (12.5)	9 (37.5)		1 (4.5)	11 (42.3)
Overall (RECIST)				0.0109			0.1405
CR + PR	19	10 (41.7)	9 (37.5)		7 (31.8)	12 (46.2)
SD + PD	10	1 (4.2)	9 (37.5)		3 (13.6)	7 (26.9)
NE	19	13 (54.2)	6 (25.0)		12 (54.5)	7 (26.9)
Primary lesions (JGCA)				0.0431			0.1405
CR + PR	25	16 (66.7)	9 (37.5)		14 (63.6)	11 (42.3)
SD + PD	23	8 (33.3)	15 (62.5)		8 (36.4)	15 (57.7)

PAN: Para-aortic node; CR: Complete response; PR: Partial response; SD: Stable disease; PD: Progressive disease; NE: Not evaluable; RECIST: Response Evaluation Criteria in Solid Tumors (version 1.1); JGCA: Japanese Gastric Cancer Association.