Nested case-control study on risk factors for opportunistic infections in patients with inflammatory bowel disease

Table 2 Demographic and clinical features of inflammatory bowel disease patients with (cases) and without (controls) opportunistic infection

	Cases (n = 70)	Controls (n = 140)	P-value
Median age	45.67 ± 15.79	44.13 ± 14.21	0.45
Gender			0.11
Male	39	89
Female	31	51
Type of IBD			0.82
UC	33	66
Proctitis	4	24
Left-sided	7	15
Extensive	22	27
CD	37	74
Ileitis (L1)	9	23
Colitis (L2)	6	3
Ileocolitis (L3)	17	26
Upper gastrointestinal tract (L4)	1	4
L1 + L4	0	5
L2 + L4	0	2
L3 + L4	4	11
Duration of IBD (yr)	6.42 ± 6.01	5.12 ± 4.04	0.28
Duration of medication (yr)	2.73 ± 2.02	2.54 ± 2.11	0.71
Prior surgery	25	41	0.31
Smoking	2	13	0.11

L1; Ileitis; L2: Colitis; L3: Ileocolitis; L4: Upper gastrointestinal tract; IBD: Inflammatory bowel disease; UC: Ulcerative colitis; CD: Crohn’s disease.