Recent advances in gastric cancer early diagnosis

doi:10.3748/wjg.v25.i17.2029

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May 7, 2019 (publication date) through Apr 28, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. May 7, 2019; 25(17): 2029-2044
Published online May 7, 2019. doi: 10.3748/wjg.v25.i17.2029

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Figure 2 Methylation changes in gastric cancer. Epigenetic alteration by methylation occurs in specific genes involved in various processes such as cell cycle regulation, DNA repair, cell growth/differentiation, transcriptional regulation, cell adhesion/invasion/migration, apoptosis, angiogenesis, as well as in multidrug resistance genes, and in genes associated with Epstein-Barr virus-type tumors or Helicobacter pylori positive tumors. These gene alterations are correlated with tumor size, localization, differentiation, invasion, lymph node metastasis, distant metastasis, TNM stage, and prognosis. GC: Gastric cancer.

Citation: Necula L, Matei L, Dragu D, Neagu AI, Mambet C, Nedeianu S, Bleotu C, Diaconu CC, Chivu-Economescu M. Recent advances in gastric cancer early diagnosis. World J Gastroenterol 2019; 25(17): 2029-2044
URL: https://www.wjgnet.com/1007-9327/full/v25/i17/2029.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i17.2029