Repurposing drugs to target nonalcoholic steatohepatitis

doi:10.3748/wjg.v25.i15.1783

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Apr 21, 2019 (publication date) through Apr 24, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Apr 21, 2019; 25(15): 1783-1796
Published online Apr 21, 2019. doi: 10.3748/wjg.v25.i15.1783

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Figure 5 The complexity of molecular targets and novel nonalcoholic steatohepatitis drugs: Pleiotropy assessed in the PheWAS United Kindom Biobank. Figure shows associations between gene variants in five nonalcoholic steatohepatitis-related molecular targets (MAP3K5/ASK1, FXR, PPARα/δ, THRβ, and MPC1) with different traits and phenotypes in the UK-PheWAS (Phenome-wide association study). Information regarding single nucleotide polymorphisms and associations were retrieved from the United Kindom Biobank (http://geneatlas.roslin.ed.ac.uk/).

Citation: Sookoian S, Pirola CJ. Repurposing drugs to target nonalcoholic steatohepatitis. World J Gastroenterol 2019; 25(15): 1783-1796
URL: https://www.wjgnet.com/1007-9327/full/v25/i15/1783.htm
DOI: https://dx.doi.org/10.3748/wjg.v25.i15.1783