Basic Study
Copyright ©The Author(s) 2019.
World J Gastroenterol. Apr 21, 2019; 25(15): 1840-1853
Published online Apr 21, 2019. doi: 10.3748/wjg.v25.i15.1840
Table 1 Correlations of Beclin1, LC3, and 4E-BP1 expression with clinicopathological characteristics in 68 advanced colorectal cancer patients n (%)
Variablen = 68Beclin1 expression
LC3 expression
4E-BP1 expression
LowHighP-valueLowHighP-valueLowHighP-value
Sex0.0610.3720.571
Male44 (64.7)13241225828
Female24 (35.3)217415316
Age (yr)0.1190.1670.865
< 6555 (80.9)10351134935
≥ 6513 (19.1)565629
Family history of cancer0.5930.1510.382
Yes13 (19.1)281919
No55 (80.9)133315311035
Location10.8621.0000.634
Left50 (73.5)11311230233
Right18 (26.5)410410911
Pathological grade0.3490.34980.897
1 + 244 (64.7)830830829
318 (26.4)510510312
NA6 (8.9)
T stage0.6180.6180.911
T1 + T2 + T341 (60.3)924924626
T422 (32.4)415415416
NA5 (7.3)
N stage0.0580.0580.654
No22 (32.4)6969412
N1 + N236 (52.9)528528625
NA10 (14.7)
Synchronous/metachronous metastasis0.0200.0580.162
Synchronous metastasis24 (35.3)118217512
Metachronous metastasis43 (63.2)13231323532
NA1 (1.5)
KRAS0.0440.0440.651
Wild type45 (66.2)13241324730
Mutant type10 (14.7)090926
NA13 (19.1)