Diffusion-weighted magnetic resonance imaging and micro-RNA in the diagnosis of hepatic fibrosis in chronic hepatitis C virus

Table 5 The cut-off values of apparent diffusion coefficient and micro-RNAs used to differentiate early from late fibrosis with areas under the receiver operating characteristic curves, sensitivity, specificity and accuracy

Parameter	AUC	Cut-off point	Sensitivity	Specificity	Accuracy
ADC	0.866	1.53	99.0%	67.0%	81.7%
miR-200b	0.888	3.55	90.6%	59.5%	73.5%
miR-21	0.877	2.38	91.7%	70.3%	80.2%
miR-29b	0.832	0.70	87.5%	60.7%	73%
ADC and miR-200b	0.925	-	71.7%	97.2%	80.2%
ADC and miR-21	0.88	-	72.3%	97.5%	83.2%
ADC and miR-29b	0.879	-	74%	96.5%	85.1%

AUC: Area under the curve; miR: Micro-RNAs; ADC: Apparent diffusion coefficient.