Phenotypic and genotypic characterization of inflammatory bowel disease in children under six years of age in China

Table 1 Clinical features of dead very-early-onset inflammatory bowel disease patients

Patient	Sex	Age of disease onset	Chief complaints	Perianal diseases	EIMs	Colonoscopy features	Disease cause death	Genetic diagnosis
1	M	Neonate	Diarrhea	Perianal abscess and fistula	Arthritis, oral ulcers	Pancolitis, ulcers and hyperplasia	Lymphoma	NA
2	M	2 mo	Diarrhea, bloody stools	None	None	Proctitis, linear and aphthous ulcers	Suspension of treatment	NA
3	M	1 yr 5 mo	Diarrhea, bloody stools	Perianal abscess	None	Pancolitis and terminal ilium ulcers and hyperplasia	Suspension of treatment	NA
4	F	3 yr 10 mo	Abdominal pain	None	None	Pancolitis, ulcers and cobble stone appearance of colon	Sepsis, multiple organ failure	NA
5	M	4 yr 11 mo	Diarrhea, bloody stools, fever, malnutrition	None	Rash, oral erosion	Pancolitis, erosion, ulcers and multiple hyperplasia lesions	Intestinal bleeding	NA
6	M	2 mo 13 d	Diarrhea, fever	Perianal abscess	None	Proctitis, longitudinal ulcer	Sepsis and shock	CGD

EIMs: Extraintestinal manifestations.