Health-related quality of life, anxiety, depression and impulsivity in patients with advanced gastroenteropancreatic neuroendocrine tumours

Table 4 Comparison of responses in patients with and without carcinoid syndrome in the HRQoL QLQ-GI.NET21 questionnaire

	Without carcinoid syndrome		With Carcinoid syndrome		Difference between groups	P value
	Mean score	(95%CI)	Mean score	(95%CI)
Endocrine symptoms	16.7	8.4-24.9	28.4	18.1-38.8	-11.8	0.04
Gastrointestinal symptoms	18.9	12.7-25.3	24.0	16.5-31.5	-5.1	0.37
Treatment-related symptoms	17.5	8.6-26.4	10.1	4.1-16.2	7.4	0.20
Social functioning	60.0	50.0-70.0	68.4	58.7-78.1	-8.4	0.19
Disease-related worries	56.9	43.0-70.8	38.7	26.2-51.2	18.2	0.05
Body image	15.3	4.3-26.2	13.3	2.1-24.6	1.9	0.57
Weight gain	18.7	7.4-30.0	13.3	2.1-24.6	5.3	0.30
Muscle/bone pain	41.3	28.6-54.1	46.7	31.3-62.1	-5.3	0.62
Information	10.7	2.0-19.3	16.0	4.7-27.3	-5.3	0.51
Sexual functioning	60.8	35.6-85.9	68.4	47.4-89.5	-7.6	0.82