Health-related quality of life, anxiety, depression and impulsivity in patients with advanced gastroenteropancreatic neuroendocrine tumours

Table 3 Comparison of responses in patients with and without carcinoid syndrome in the HRQoL QLQ-C30 questionnaire

	Without carcinoid syndrome		With Carcinoid syndrome		Difference between groups	P value
	Mean score	(95%CI)	Mean score	(95%CI)
Global health status	63	52.3-73.7	61.7	49.6-73.7	1.3	0.92
Physical functioning	79.9	73.0-86.8	77.9	67.9-87.9	2.0	0.79
Role functioning	74	61.3-86.7	70.7	56.3-85.0	3.3	0.77
Emotional functioning	73	63.0 – 83.0	74.7	63.7-85.6	-1.7	0.73
Cognitive functioning	76.7	66.3-87.0	74.0	61.0-87.0	2.7	0.93
Social functioning	70	58.6- 81.4	79.3	67.2-91.5	-9.3	0.15
Fatigue	34.7	23.6-45.8	37.8	23.9-51.7	-3.1	0.84
Nausea and vomiting	11.3	4.0-18.7	8.00	1.4-14.6	3.3	0.31
Pain	25.3	11.8-38.8	26.7	13.5-39.8	-1.3	0.81
Dyspnoea	12.5	1.7-23.3	24.0	10.5-37.5	-11.5	0.15
Insomnia	36	22.9-39.1	22.7	10.9-34.3	13.3	0.12
Appetite loss	18.7	8.1-29.2	22.7	9.7-35.7	-4	0.81
Constipation	9.3	1.9-16.8	9.30	1.9-16.8	0	1.00
Diarrhoea	24	9.4-38.6	32.0	17.4-46.6	-8.0	0.27
Financial difficulties	13.3	3.6-23.1	8.00	-18.2	5.3	0.30

HRQoL: Health-related quality of life.